The baculovirus–insect cell expression system — insect cells used in conjunction with the baculovirus expression vector system (BEVS) —  remains a crucial technology for manufacturing large and complex proteins. This eukaryotic expression system offers inherent safety, ease of scale-up, flexible product design, and versatility for a broad range of proteins. This Insight from Industry Report features comments from Amy Sheng, currently Chief Research Officer at Sino Biological, who received her Ph.D. in Molecular and Cell Biology in 2017 from the School of Biological Sciences.